Abstract: Whether Foucault moved to focus on the biopower of body and population by getting rid of the power analysis type of the “Leviathan model”,or Agamben placed the relationship between the state of nature and the state of exception in a topological structure,and Esposito reinterpreted the internal principles of the operation of the “Leviathan” by metonymizing the immune category in the medical field,The Hobbes element is an important link in the construction and promotion of the theory of Biopolitics.Analyzing the Hobbes element in biopolitics can not only present the theoretical origin relationship between biopolitics and modern political philosophy in the context of intellectual history,but also present its unique problem domain and explanatory power in the context of the theoretical development of biopolitics itself.