Abstract: The purpose of reintroducing the interdisciplinary practice in the field of Chinese children’s literature is to reexamine the ontological meaning of its concept from the perspective of discipline boundaries and explore the knowledge basis of interdisciplinary expansion, based on the endogenous and exogenous isomorphism of the development of literature. Chinese children’s literature is not only a descriptive concept, but also a concept of structure and relationship. This kind of concept and the particularity of the subject drive the inter-disciplinary turn intrinsically. In general, the interdisciplinary development path of Chinese children’s literature includes two levels: internal linkage and external linkage. In the world of children’s literature and the overall situation of the Chinese literature in hundred years, this kind of practice across into the system theory field of vision, beyond “pure literature essence doctrine” and “non-literary instrumentalism” theory of intolerance, effectively while its stay open dialogue and exchanges among disciplines, with Rio tinto domain to promote the integration of subject knowledge, and Chinese children’s literature to develop in the direction of depth.